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Ovarian cancer study points to a metabolic weak spot in chemo resistance
Researchers report that a metabolite-linked pathway helps some ovarian tumors repair DNA damage and survive platinum chemotherapy, revealing a potential way to weaken treatment resistance.
Key Takeaways
- Researchers linked chemotherapy resistance in some ovarian cancers to a metabolic pathway involving alpha-ketoglutarate.
- The study identified TMLHE as an enzyme connected to tumor DNA repair capacity.
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DT Editorial Team··via medicalxpress.com