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Stroke May Remodel Brain Cells in Ways That Help Gliomas Grow
Key Takeaways
- Researchers at Texas Children's Duncan NRI and Baylor College of Medicine, with collaborators, published the findings in Nature Cancer.
- Stroke promoted glioma infiltration into injured brain regions in both human and mouse models and was linked to reduced overall survival.
- The team identified a distinct population of tumor-associated astrocytes (TAAs) with diminished calcium activity appearing after stroke.
- TAAs were accompanied by accumulation of remodeled tumor-associated microglia and macrophages (TAMs).
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DT Editorial Team··via medicalxpress.com
