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Researchers Say a Fat-Burning Protein Also Protects Fat Cells From Within the Nucleus
New work reported in Cell Metabolism suggests hormone-sensitive lipase has a second role inside adipocyte nuclei, helping explain why loss of the protein leads to lipodystrophy rather than obesity.
Key Takeaways
- Researchers reported that hormone-sensitive lipase operates inside adipocyte nuclei as well as on lipid droplets.
- The finding may explain why HSL loss leads to lipodystrophy rather than obesity in mice and people with mutations.
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