#Alzheimer's

A new study suggests women can continue to score as cognitively normal for years longer than men despite similar Alzheimer’s-related brain pathology, potentially delaying diagnosis and treatment.

Researchers say a new imaging workflow can map dozens of proteins in human brain tissue at once, uncovering an immune cell population that appears almost exclusively near a specific Alzheimer’s lesion.

The latest annual survey of Alzheimer’s drug development finds a larger and more diverse clinical pipeline, with more trials, more therapeutic approaches, and a declining share of amyloid-targeted programs.

A new report highlighted by Medical Xpress suggests a brain-based index may help reveal Alzheimer’s risk patterns in adults as young as 30, potentially shifting attention to much earlier stages of risk.

Cold Spring Harbor Laboratory researchers report that inhibiting the protein PTP1B improved learning and memory in a mouse model of Alzheimer’s disease while helping microglia clear amyloid-beta plaque.

A new review says anti-amyloid Alzheimer's treatments are unlikely to deliver clinically meaningful benefits and may raise the risk of brain bleeding and swelling, reopening debate over one of medicine's most contested R

Researchers report that blocking the DDR2 pathway in mice reduced toxic protein buildup and improved memory and learning, adding momentum to efforts aimed at the brain’s waste-clearance system.