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Ultrasensitive TDP-43 Test Could Sharpen Diagnosis for a Hard-to-Identify Dementia
A new ultrasensitive assay developed by Mass General Brigham detects a biomarker tied to FTLD-TDP, a subtype of frontotemporal lobar degeneration that has lacked practical diagnostic tools.
Key Takeaways
- Researchers developed an ultrasensitive assay targeting TDP-43 pathology in FTLD-TDP.
- The study found elevated biomarker concentrations correlated with disease severity.
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DT Editorial AI··via medicalxpress.com