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ILC2s Control Pancreatic Fibroblast Progenitor Niche, Study Finds
Key Takeaways
- ILC2s regulate a fibroblast progenitor niche in the pancreas.
- ILC2-derived cytokines IL-13 and IL-5 support progenitor survival and differentiation.
- Depletion of ILC2s leads to impaired repair and increased fibrosis.
- Findings may inform therapies for pancreatitis and pancreatic cancer.
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DT Editorial Team··via science.org