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Transcriptome-Based Classification Maps Autism Risk Mutations in Mice
Key Takeaways
- Science published "Transcriptome-based classification in mice with ASD-risk mutations" in Volume 393, Issue 6817, pages 1250–1257 (September 2026).
- The method groups mice by gene-expression profiles instead of by the specific autism-risk mutation they carry.
- Transcriptomes reflect both genetic variation and environmental influence, offering a dynamic readout of biological state.
- Mouse models permit controlled, developmentally precise profiling but cannot directly translate to human diagnosis or treatment.
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DT Editorial Team··via science.org